2021 Impact factor 3.131
Hadrons and Nuclei


Eur. Phys. J. A 13, 189-195 (2002)

New life science studies with muons and radioactive nuclei

K. Nagamine

Muon Science Laboratory, Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan Meson Science Laboratory, Institute of Materials Structure Science (KEK), 1-1 Oho, Tsukuba, Ibaraki 305-0801, Japan

(Received: 1 May 2001 / Revised version: 28 June 2001 )

Abstract
Electron-transfer phenomena in biological macromolecules are among the most important processes in physics. Since there are no "radioactive electrons", a limited number of microscopic studies exist, and thus most knowledge is based upon macroscopic studies. In order to overcome this situation, a muon-labelled electrons method was recently developed and successfully applied to directly exploring microscopic electron-transfer phenomena in representative proteins, such as cytochrome-c, cytochrome-c oxidase and myoglobin as well as DNA. The principle and some details of each experiment are reviewed. A possible extension to the labelled-electron method with radioactive nuclei is discussed.

PACS
76.75.+i - Muon spin rotation and relaxation.
87.15.-v - Biomolecules: structure and physical properties.
87.66.Uv - Magnetic resonance.

© Società Italiana di Fisica, Springer-Verlag 2002

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